HBV Resistance
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All the information provided here including recommendations and suggestions should be treated for informational purposes only and not a coercion to follow.
The author should not be held liable for any informational errors, incompleteness, delays or for any actions taken in reliance on information contained here.
Lamivudine Resistance:
- Add ADV / TDF
- Switch Truvada
Adefovir Resistance:
- Add LMV
- Switch Truvada
- Switch to / Add ETV
Entecavir Resistance:
- Switch to TDF / Truvada
Telbivudine Resistance:
- Add ADV / TDF
- Switch Truvada
|
LMV |
LdT |
ETV |
ADV |
TDF |
Wild Type |
S |
S |
S |
S |
S |
M204I |
R |
R |
I/R |
S |
S |
L180M + M204V |
R |
R |
I |
S |
S |
A181T / V |
I |
S |
S |
R |
S |
N236T |
S |
S |
S |
R |
I |
L180M + 204V/I +/- I169T +/-V173L +/- M250V |
R |
R |
R |
S |
S |
L180M + 204V/I +/- T184G +/-S202I/G |
R |
R |
R |
S |
S |